LIFE AT Achilles

At Achilles, we are focused on the development of the next generation of personalised immunotherapies to treat cancer and are dedicated to our patients, who desperately need breakthrough medicines.

We provide extraordinary career opportunities for talented individuals, who will have the opportunity to work with highly experienced leaders in science and business to build an exciting company at the very cutting edge of cancer medicine.

At Achilles you will enjoy a flexible and dynamic working environment that fosters creativity, leadership and teamwork. We offer benefits that include competitive salary and performance related bonus, group pension plan, life assurance, private medical insurance and employee share incentive scheme.

If you have what it takes to help build Achilles into a world class immune-oncology company and would like to become a part of our team, please contact: jobs@achillestx.com.

Achilles is an equal opportunity employer committed to a culturally diverse team.

Recruiters and agents must not forward CVs or candidate details to Achilles or any employee of the Company without an explicit, written request from a member of the HR department. We reserve the right to pursue and hire candidate(s) without any financial obligation to the recruiter if their details, which could reasonably identify them, have been passed to the Company without the explicit, written request of a member of the HR department. The agreement of terms in relation to a specific vacancy does not constitute an explicit request for applicants for other advertised roles or speculative applications.

What Our Team Say

I was attracted to Achilles by the ambition of the science that underlies Achilles’ goal. I enjoy the fast-paced environment of a start-up, encountering new challenges on a daily basis. Achilles has a multicultural and cohesive culture with a very strong sense of purpose.

Eleni Kotsiou

Principal Scientist, Process Development

I joined Achilles because I am interested in developing a cancer immunotherapy product with the aim of taking it to clinic. I really enjoy working within a multidisciplinary team and the variety in my role across process development and manufacturing.

Sam Jide-Banwo

GMP Production Scientist

Open PositionsAt Achilles

Medical Director, Clinical Development

About Achilles Therapeutics:
Achilles Therapeutics is a company focused on the development of T cell therapies tar-geting clonal neoantigens for the treatment of cancer. We use DNA sequencing data from each patient, together with our proprietary PELEUS™ bioinformatics platform, to identify clonal neoantigens specific to that patient and develop personalised T cell ther-apies. Originating from pioneering research at UCL, CRUK and the Francis Crick Insti-tute, we are using our ground-breaking immuno-oncology approach to rapidly advance therapies, with our first products for Non-Small Cell Lung Cancer and melanoma expected to enter the clinic in 1H 2020.

Role:
We are seeking a Medical Director, Clinical Development with experience working in oncology or haematological malignancies, to join our growing company and support the development of a next generation personalised cancer medicine. As a Medic at Achilles Therapeutics, you will report directly to the Chief Medical Officer and work closely with other members of the senior leadership team to deliver the medical strategy and establish overall benefit, risk and value of ATL001 as well as future therapies.

Responsibilities:

Study Level Tasks:
• Medical monitoring activities e.g:
• Review subject eligibility and protocol deviations; respond to site queries
• Train site teams and CRAs in the relevant therapy area, clinical study protocol and investigational product
• Conduct regular medical review of safety, coding, labs and efficacy data to ensure accuracy and consistency
• Ensure data quality ahead of database locks for interim analyses of safety and efficacyContribute to writing clinical protocols and other study-related documents
• Ensure rapid SAE processing and documentation (assessment, relatedness, queries, narratives)

Clinical Development Tasks:
• Contribute to the Clinical Development Strategy
• Contribute to the design and interpretation of clinical studies
• Ensure the safety of patients participating in all clinical trials of ATL001
• At the request of the CMO, represent Achilles in interactions with external stakeholders (e.g., regulatory authorities, pricing and reimbursement bodies, key opinion leaders, advisory boards, potential industry partners, potential Investors, patient advocacy groups), and internal stakeholders (e.g., CEO, Scientific Founders, Board members)
• Contribute to the delivery of the translational science strategy
• Effectively communicate project status, risks and issues to CMO
• Contribute to writing clinical components of regulatory documents (e.g., Investigators’ Brochure, DSUR, clinical components of regulatory submissions
• Contribute to writing abstracts, presentations, and manuscripts

Education and Experience:
• MD or PhD with expertise in oncology or haematological malignancies, and relevant experience of clinical trials in either an industry or academic setting
• Excellent scientific and analytical skills
• Excellent interpersonal skills, with demonstrated ability to interact effectively with peers and a variety of stakeholders
• Desirable but not essential: experience in immune-oncology or cell and gene therapies

This is a permanent position, initially based in Stevenage but relocating to West London in 2020. This position offers a competitive salary and benefits package

The role offers a competitive salary and benefits package to match experience.

Please send your CV with a covering letter by clicking Apply.

Senior Bioinformatician

About Achilles Therapeutics:
Achilles Therapeutics is a company focused on the development of T cell therapies targeting clonal neoantigens for the treatment of cancer. We use DNA sequencing data from each patient, together with our proprietary PELEUS™ bioinformatics platform, to identify clonal neoantigens specific to that patient and develop personalised T cell therapies. Originating from pioneering research at UCL, CRUK and the Francis Crick Institute, we are using our ground-breaking immuno-oncology approach to rapidly advance therapies, with our first products for Non-Small Cell Lung Cancer and melanoma expected to enter the clinic in 1H 2020.

Role Summary:
We are seeking a highly talented and creative Senior Bioinformatician. The successful applicant will join a small team primarily focused on improving and developing methods to identify neoantigens. You will be expected to proficiently identify and benchmark published tools as well as contribute to the development of novel strategies. You will also design, implement, and apply statistical techniques to analyse and integrate large datasets and work in close collaboration with biologists and clinicians to interpret your analysis results.
This is a unique opportunity to work with a leading team of scientists with an international reputation for excellence in immuno-oncology research and to become a key contributor to an exciting project destined to change the course of cancer patient management in the clinic.

Responsibilities:
• Integration and exploratory data analysis of large, complex datasets
• Develop and test hypotheses whilst prototyping analytical approaches/models
• Develop scalable tools
• Effectively communicate analyses to a technical and non-technical audience

This position requires:
• PhD and 2+ years of relevant work experience in bioinformatics, computational biology, or equivalent
• Good knowledge of molecular genomics and immunology
• Knowledge of advanced statistical & machine learning concepts
• Practical experience of analysing next generation sequencing data (DNA and RNA)
• Authorship on high-quality papers in peer-reviewed journals
• Demonstrated fluency in R and Python
• Experience in reproducible research practices (e.g. dynamic documents, version control, containerization & workflow engines)
• Extensive knowledge of UNIX based operating systems

In addition to the above, you are expected to have:
• Exceptional communication skills
• Demonstrable excellence in problem solving within fixed timelines
• Flexibility and the ability to effectively manage multiple concurrent projects

In addition to the above, the following skills/experiences are desirable:
• Practical experience of oncogenomic, immunogenomic, neoantigen and/or TCR-seq analyses
• Practical experience with cloud-based technologies

This is a permanent position, based in Stevenage, with a competitive salary and benefits package.

Please send your CV with a covering letter by clicking Apply.

Computational Biologist

About Achilles Therapeutics:
Achilles Therapeutics is a company focused on the development of T cell therapies targeting clonal neoantigens for the treatment of cancer. We use DNA sequencing data from each patient, together with our proprietary PELEUS™ bioinformatics platform, to identify clonal neoantigens specific to that patient and develop personalised T cell therapies. Originating from pioneering research at UCL, CRUK and the Francis Crick Institute, we are using our ground-breaking immuno-oncology approach to rapidly advance therapies, with our first product for Non-Small Cell Lung Cancer expected to enter the clinic in 1H 2020.

Role Summary:
We are seeking a talented and enthusiastic computational biologist to join the Sequence Data Analysis team within the Bioinformatics group. This team is responsible for the analysis of large best-in-class biological datasets with an aim to help guide and develop methodologies to improve our ability to identify therapeutically relevant clonal neoantigens. Collaborating closely with other biologists and clinicians you will also be tasked with the design, implementation and analysis of novel protocols to improve our current sequencing workflow.
This is a unique opportunity to join a company in an exciting start-up phase that has the ability to transform the clinical management of cancer.

Responsibilities:
• Integration and exploratory data analysis of large, complex datasets
• Develop and test hypotheses whilst prototyping analytical approaches
• Provide support to different working groups for their NGS based projects
• Effectively communicate analyses to a technical and non-technical audience

This position requires:
• PhD or MSc and 2+ years of relevant work experience in bioinformatics, computational biology, or equivalent
• Extensive knowledge of cancer genomics
• Advanced mathematics with strong experience of applied statistical modelling, ideally gained from next generation sequencing data applications
• Practical experience of analysing next generation sequencing data
• Demonstrated fluency in R and/or Python
• Extensive knowledge of UNIX based operating systems
• Exceptional communication skills
• Demonstrable excellence in problem solving within fixed timelines
• Flexibility and the ability to effectively manage multiple concurrent projects

This is a permanent position, based in Stevenage/London, with a competitive salary and benefits package.

Please send your CV with a covering letter by clicking Apply.

GCLP Research Associate

About Achilles Therapeutics:
Achilles Therapeutics is a company focused on the development of T cell therapies tar-geting clonal neoantigens for the treatment of cancer. We use DNA sequencing data from each patient, together with our proprietary PELEUS™ bioinformatics platform, to identify clonal neoantigens specific to that patient and develop personalised T cell ther-apies. Originating from pioneering research at UCL, CRUK and the Francis Crick Insti-tute, we are using our ground-breaking immuno-oncology approach to rapidly advance therapies, with our first products for Non-Small Cell Lung Cancer and Melanoma expected to enter the clinic in 1H 2020.

Role:
We are seeking a scientist with experience working with immunoassays, to join our growing company and support the development of a next generation personalised cancer medicine. As a GCLP Research Associate at Achilles Therapeutics, you will report directly to the Translational Science Principal Scientist and work closely with other members of the Translational Science team to carry out assays on human samples from clinical trials at Achilles Therapeutics at both Stevenage and London sites.
The successful candidate will have a role in sample receipt, carrying out immunoassays, and maintaining the GCLP laboratory. They will have experience working with human blood samples, including PBMC isolation and cell cryopreservation and in flow cytometry. Experience of working in a GCLP or GxP environment is essential.
If you want to be a part of a well-funded, exciting new start-up, and enjoy contributing to development of products which will transform the clinical management of cancer, then this is the role for you.

Responsibilities:
• Receive and process cryopreserved samples from Achilles clinical trials
• Carry out immunoassays including multi-parameter flow cytometry and ELISpot
• Complete all relevant documentation in accordance with GCLP guidelines
• Prepare slides and curls from FFPE tissue blocks
• Carry out DNA and RNA extraction protocols
• Maintain laboratory equipment as required
• Follow established SOPs
• Record sample and analysis data accurately
• Support the Translational Science team at the RFH, London with receipt, processing and banking human samples from Achilles clinical trials, as required

Education and Experience:
• Hands-on laboratory experience
• Undergraduate degree in a biological subject
• Experience working with human blood samples, including PBMC isolation using density centrifugation
• Experience with immunoassays including multi-parameter flow cytometry
• Experience working in a GCLP (or GxP) laboratory
• Excellent planning, organisational and time management skills, and attention to detail
• Good communication and interpersonal skills
• Self-motivated with strong initiative and drive
• Ability to work flexibly across both Achilles sites, and including evenings and weekends, as required
• Proficiency with MS Office

Skills
• Master’s degree in a relevant subject
• Experience working with liquid nitrogen
• Practical experience of working with and/or set up of a LIMS system
• Knowledge of cancer biology and immunology

This is a permanent position based at Stevenage Bioscience Catalyst in Hertfordshire, with the requirement for work at the Royal Free Hospital site in London, as required.

The role offers a competitive salary and benefits package to match experience.

Please send your CV with a covering letter by clicking Apply.

Data Manager

About Achilles Therapeutics:
Achilles Therapeutics is a company focused on the development of T cell therapies targeting clonal neoantigens for the treatment of cancer. We use DNA sequencing data from each patient, together with our proprietary PELEUS™ bioinformatics platform, to identify clonal neoantigens specific to that patient and develop personalised T cell therapies. Originating from pioneering research at UCL, CRUK and the Francis Crick Institute, we are using our ground-breaking immuno-oncology approach to rapidly advance therapies, with our first products for Non-Small Cell Lung Cancer and Melanoma entering the clinic in 1H 2020.

Role Summary:
Achilles Therapeutics is looking for an experienced Data Manager to join our Translational Science team. This team is responsible for the development and delivery of analyses that turn exploratory hypotheses into actionable insights from our clinical trial data.The Data Manager role at Achilles will be crucial for ensuring data integrity from the management of Translational laboratory activities through to the processing and reliable storage of data outputs for Translational Science analyses.

The successful candidate will:
• Assume responsibility for co-ordinating data output from different Translational assays through the data lifecycle to ensure reliable insertion into Achilles’ proprietary Translational databases and data integrity
• Assume responsibility for administering and configuring a new LIMS system to aid sample and laboratory management and recording of outputs from Translational Science activities.

This position requires:
• BSc or MSc in Computer Science or a relevant informatics subject
• Experience in organising and transferring large volumes of data securely and robustly
• Demonstrated fluency in a general programming language (Python)
• Understanding and experience of Relational Databases and SQL
• Experience of handling biological datasets

In addition to the above, you are expected to have:
• Strong organisational skills and a desire to take responsibility for all aspects of the data lifecycle
• Passion for processing and delivering clean data for downstream analyses
• Exceptional time management agility to manage concurrent data flows
• Excellent communication skills and the ability to work cross-functionally

With the following skills/experiences desirable:
• Understanding of clinical trial data requirements

This is a permanent position, based in the Stevenage Bioscience Catalyst, with a competitive salary and benefits package.

Please send your CV with a covering letter by clicking Apply.

Financial Controller

About Achilles Therapeutics:
Achilles Therapeutics is a company focused on the development of T cell therapies targeting clonal neoantigens for the treatment of cancer. We use DNA sequencing data from each patient, together with our proprietary PELEUS™ bioinformatics platform, to identify clonal neoantigens specific to that patient and develop personalised T cell therapies. Originating from pioneering research at UCL, CRUK and the Francis Crick Institute, we are using our ground-breaking immuno-oncology approach to rapidly advance therapies, with our first products for Non-Small Cell Lung Cancer and Melanoma expected to enter the clinic in 1H 2020.

Role Summary:
Achilles is looking to hire a Financial Controller to take responsibility for financial controls and transaction processing within the Company, heading up the team responsible for the day to day financial activities of the Company.
The Controller will be a key member of the Finance team and will be required to work closely with senior stakeholders both within and outside the business.

Responsibilities and Duties
• Manage day to day financial activities including financial ledgers, payroll and cash management.
• Oversee period close processes producing high quality monthly management accounts and quarterly investor reporting
• Oversee the preparation of year-end statutory accounts: currently UK entity accounts only but envisaged to include international subsidiaries and consolidated UK Group accounts as the Company expands its operations in the future
• Ensure all reporting is prepared on a timely basis and in accordance with the relevant accounting standards (FRS102 or US GAAP) as well as company requirements
• Co-ordinate and manage the audit process ensuring the Company adheres to its strict year end reporting timetable
• Develop, document and implement enhancements to the control environment including enhancements to the finance system: Achilles is currently implementing NetSuite and the Controller will need to oversee training and roll out of additional functionality including automation of manual processes
• Implement the Company treasury policy with an appropriately structured liquidity ladder
• Provide tax and compliance support

Education and Experience
• Degree qualified or equivalent
• Qualified accountant
• Up-date technical skills and confident preparing UK statutory accounts under local UK GAAP
• Strong working knowledge of US GAAP and SOX (highly desirable)
• Experience of having worked in recognised and reputable audit practice prior to working in industry (desirable)
• Experience of having worked in a listed company environment

Skills
• Strong focus on controls and processes and a high attention to detail
• Demonstrated ability to thrive in a dynamic and fast-paced environment in organisation undergoing rapid scale-up
• Credible finance professional able to command the respect and trust of both management and staff – The Controller will need to be able to drive through process changes winning buy-in from the business
• Strong written and verbal communication skills – The Controller will engage with colleagues on a daily basis and will need to ensure processes and standards are being followed
• Highly developed teamwork skills. This role requires working across all areas of the business and with other members of the finance team.
• Excellent project management skills

This is a permanent position, initially based in Stevenage but relocating to West London in 2020. This position offers a competitive salary and benefits package

Please send your CV with a covering letter by clicking Apply.

Senior Manager, FP&A

About Achilles Therapeutics:
Achilles Therapeutics is a company focused on the development of T cell therapies targeting clonal neoantigens for the treatment of cancer. We use DNA sequencing data from each patient, together with our proprietary PELEUS™ bioinformatics platform, to identify clonal neoantigens specific to that patient and develop personalised T cell therapies. Originating from pioneering research at UCL, CRUK and the Francis Crick Institute, we are using our ground-breaking immuno-oncology approach to rapidly advance therapies, with our first products for Non-Small Cell Lung Cancer and Melanoma expected to enter the clinic in 1H 2020.

Role Summary:
Achilles is establishing a dedicated FP&A function with the hiring of a Senior Manager, FP&A to support the scale up and growing complexity of the business. The Manager will be required to ensure that FP&A function oversees a robust budget setting and reforecasting process to manage Board, Investor and other key stakeholder expectations appropriately.
The Manager will be a key member of the Finance team and will influence and guide financial and business decisions. The Manager will serve as a business partner to the management team both challenging and informing the management team and rolling out appropriate training for all those involved in the budgeting process.

Responsibilities:
• Take ownership of the annual budgeting process collaborating and partnering across the business to develop the annual budgets and forecast updates
• Own the working capital model to generate robust cash utilisation forecasts and sensitivities analysis
• Further develop long range financial models to support fair value asset valuations
• Build and develop long range commercial models to support planning around product launch
• Understand the financial needs and drivers of the business and provide operational and strategic finance support to enable execution of business decisions
• Work closely with the Finance Director to generate the narrative and insight that forms part of the management, CEO, Investor and Board reporting packs
• Evaluate and implement appropriate analytical tools and software: Achilles is currently implementing NetSuite ERP and the Manager would be expected to evaluate the advanced analytical tools available within NetSuite as well as 3rd party providers that integrate with NetSuite with a view to automating and streamlining FP&A processes.
• Business partner on large R&D and capital projects

Skills required:
• Demonstrated ability to thrive in a dynamic and fast-paced environment in an organisation undergoing rapid scale-up
• Credible financial professional able to command the respect and trust of both management and staff
• Strong effective communicator in writing, business presentations and interpersonal communications. Ability to communicate technical or complex issues with clarity to non-financial individuals
• Highly developed teamwork skills. This role requires working closely across all areas of the business and with other members of the finance team.
• Data driven analytical skills
• Excellent project management skills
• Expert in financial modelling

Experience required:
• Degree qualified or equivalent
• Qualified accountant
• Experience of having worked in a pharmaceutical, biotech or pharma services environment highly desirable

This is a permanent position, initially based in Stevenage but relocating to West London in 2020. This position offers a competitive salary and benefits package.

Please send your CV with a covering letter by clicking Apply.

Regulatory Affairs Manager / Senior Manager

About Achilles Therapeutics:
Achilles Therapeutics is a company focused on the development of T cell therapies targeting clonal neoantigens for the treatment of cancer. We use DNA sequencing data from each patient, together with our proprietary PELEUS™ bioinformatics platform, to identify clonal neoantigens specific to that patient and develop personalised T cell therapies. Originating from pioneering research at UCL, CRUK and the Francis Crick Institute, we are using our ground-breaking immuno-oncology approach to rapidly advance therapies, with our first product for Non-Small Cell Lung Cancer expected to enter the clinic in 2H 2019.

Role Summary:
We are seeking a talented and driven regulatory affairs professional looking to take the next step in their career and to lead assigned regulatory activities for both research and clinical stage assets.
This is a unique opportunity to join a company in an exciting start-up phase that has the ability to transform the clinical management of cancer.

Responsibilities:
Including but not limited to:
• Provide regulatory input to development-stage specific regulatory activities including clinical trial applications and regulatory authority interactions
• Prepare regulatory documentation in accordance with global regulatory requirements
• Engage with regulatory authorities as the point of contact for designated activities
• Manage assigned projects and ensure that regulatory aspects are tracked and followed through to completion

This position requires:
• Significant experience with development stage regulatory activities
• Direct experience in the preparation of regulatory documentation for INDs/CTAs and regulatory authority meetings
• Knowledge and understanding of relevant region specific and ICH guidelines for medicinal products
• Relevant degree in a scientific or technical discipline
• Strong communication skills, both written and verbal
• Must have strong project management skills (e.g. planning, prioritization, management of schedules and timelines, detail orientation, strong sense of urgency).
• Must be able to work self-sufficiently with strong initiative.
• Ability to lead complex projects and a high degree of problem-solving capability is required

This is a permanent position, based in London, with a competitive salary and benefits package.

Please send your CV with a covering letter by clicking Apply.

Research Associate

About Achilles Therapeutics:
Achilles Therapeutics is a company focused on the development of T cell therapies targeting clonal neoantigens for the treatment of cancer. We use DNA sequencing data from each patient, together with our proprietary PELEUS™ bioinformatics platform, to identify clonal neoantigens specific to that patient and develop personalised T cell therapies. Originating from pioneering research at UCL, CRUK and the Francis Crick Institute, we are using our ground-breaking immuno-oncology approach to rapidly advance therapies, with our first products for Non-Small Cell Lung Cancer and Melanoma expected to enter the clinic in 1H 2020.

Role Summary:
We are seeking a highly motivated and committed Research Associate. The successful applicant will join a small team within the Process Development department primarily focused on gene editing of immune cells. The work will be carried out at Achilles Therapeutics in Stevenage in collaboration with Prof Sergio Quezada’s team at University College London, benefiting from their deep expertise in tumour microenvironment and immune modulation.
The post requires a driven individual with experience in immunology, flow cytometry and cell culture techniques. This is a unique opportunity to work with a leading team of scientists with an international reputation for excellence in immuno-oncology research and to join a company in an exciting start-up phase that has the ability to transform the clinical management of cancer.

Responsibilities:
• Hands-on gene editing work
• Contribute to evaluation of gene edited cells
• Follow established SOPs
• Participate in the Process Development team activities
• Effectively communicate scientific results.

This position requires:
• Degree in Immunology/Biology or relevant field (e.g., gene editing)
• 2+ years hands-on laboratory experience
• Experience with immunoassays including flow cytometry
• Good planning, organisational and time management skills, and attention to detail
• Good communication and interpersonal skills
• Self-motivated with strong initiative and drive

In addition to the above, you are expected to have:
• Experience working with patient blood and tissue samples
• Knowledge on tumour immunology or gene editing
• Master’s degree in a relevant subject.

In addition to the above, the following skills/experiences are desirable:
• Experience with gene editing techniques (e.g., CRISP/Cas9)
• Practical experience on genetic manipulation of cells (knock down and overexpression)
• Experience with functional T cell assays (eg ELISPOT, killing/ proliferation assays)

This is a two year fixed term position, initially based in Stevenage but relocating to West London in 2020.

Please send your CV with a covering letter by clicking Apply.

Principal GMP Production Scientist

About Achilles Therapeutics:
Achilles Therapeutics is a company focused on the development of T cell therapies targeting clonal neoantigens for the treatment of cancer. We use DNA sequencing data from each patient, together with our proprietary PELEUS™ bioinformatics platform, to identify clonal neoantigens specific to that patient and develop personalised T cell therapies. Originating from pioneering research at UCL, CRUK and the Francis Crick Institute, we are using our ground-breaking immuno-oncology approach to rapidly advance therapies, with our first products for Non-Small Cell Lung Cancer and Melanoma expected to enter the clinic in 1H 2020.

Role Summary:
We are seeking a well-qualified and experienced candidate to join our growing manufacturing team at Achilles Therapeutics to support the scale up of manufacturing for the Company’s personalised T cell therapy products for use across Achilles clinical trial programmes. As a Senior GMP Production Scientist you will support the technology transfer, validation and clinical production of Achilles advanced therapies and also working closely with the product development team to support process engineering activities. If you want to be a part of a well-funded, exciting new start-up, and enjoy playing an active role in supporting the development and clinical manufacture of ATMPs which have the ability to transform the clinical management of cancer, then this is the role for you.
This is a unique opportunity to join a company in an exciting start-up phase that has the ability to transform the clinical management of cancer.

Key Responsibilities:
• Supporting GMP activity for the manufacture of ATMPs to facilitate technology transfer, process validation, equipment validation and qualification, stability studies and materials management.
• Support process engineering activity in closed system cell culture and identifying and implementing procedures in accordance with GMP and regulatory standards.
• Support continued development and in-process improvement activity to streamline process operations and optimisation of manufacturing methods
• To assist/lead in the preparation and review of GMP documentation including BMRs, SOPs, Change Control, user requirement specifications, process deviations, and risk assessments to ensure the highest levels of controls and traceability
• Perform ATMP manufacturing for clinical trials and ensure all manufacturing activities are undertaken in accordance with production requirements and GMP regulatory and quality standards.
• Assist/lead in coordination of production scheduling activity, labelling, packaging and distribution of starting materials, raw materials and final drug product
• To coordinate activities with QC to ensure appropriate and timely sampling and testing of raw materials, in-process samples and finished product.
• Assist/lead in the maintenance of a laboratory environment suitable for the manufacture of ATMPs
• Work with external service providers
• Be accountable to the head of production for all production operation
• Provide support and supervision for junior GMP production scientists

This position requires:
• BSC/MSC in a Biological Science discipline.
• 5 years’ experience in a scientific laboratory role.
• Minimum of 3 years’ experience working in a regulated environment (GLP/GCLP/GMP).
• Experience in human cell isolation, and cell and tissue culture in a GMP compliant environment.
• Able to work in a Grade B cleanroom production environment.
• ATMP Process validation experience.
• Understanding of GMP, ATMP, and EUTCD regulations
• Working knowledge of generating process and QC data for regulatory submissions.
• Strongly focused on quality and safety.
• Have excellent planning and organisational and time management skills.
• Have good communication and interpersonal skills
• Self-motivated with strong initiative and drive.

This is a permanent position, based at Achilles HQ in Stevenage with the opportunity to work with the Achilles manufacturing team established at The Royal Free Hospital in London. This position offers a competitive salary and benefits package.

Please send your CV with a covering letter by clicking Apply.